Publications and Preprints

Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer

Adrian M. Gomez, Yue Wu, Chao Zhang, Leah Boyd, Tse-Luen Wee, Joseph Gewolb, Corina Amor, Lucas Cheadle, Jeremy C. Borniger

Neuron. 2025

A single-cell transcriptomic atlas of sensory-dependent gene expression in developing mouse visual cortex

Andre M. Xavier, Qianyu Lin, Chris J. Kang, Lucas Cheadle

Development. 2025

High-confidence and high-throughput quantification of synapse engulfment by oligodendrocyte precursor cells

Jessica A. Kahng, Andre M. Xavier, Austin Ferro, Samantha X. Tang, Yohan S. S. Auguste, Lucas Cheadle

Nature Protocols. 2024

A brain-body feedback loop driving HPA-axis dysfunction in breast cancer

Adrian Gomez, Yue Wu, Chao Zhang, Leah Boyd, Tse-Luen Wee, Joseph Gewolb, Corina Amor, Lucas Cheadle, Jeremy C. Borniger

Preprint. 2024

A single-cell transcriptomic atlas of sensory-dependent gene expression in developing mouse visual cortex

Andre M. Xavier, Qianyu Lin, Chris J. Kang, Lucas Cheadle

Preprint.     2024

The cytokine receptor Fn14 is a molecular brake on neuronal activity that mediates circadian function in vivo

Austin Ferro, Anosha Arshad, Leah Boyd, Tess Stanley, Adrian Berisha, Uma Vrudhula, Adrian M. Gomez, Jeremy C. Borniger, Lucas Cheadle

Preprint.     2024

Disruption of Cholinergic Retinal Waves Alters Visual Cortex Development and Function

Timothy J Burbridge, Jacob M Ratliff, Deepanjali Dwivedi, Uma Vrudhula, Francisco Alvarado-Huerta, Lucas Sjulson, Leena Ali Ibrahim, Lucas Cheadle, Gordon Fishell, Renata Batista-Brito

Preprint.     2024

Emerging roles of oligodendrocyte precursor cells in neural circuit development and remodeling

Buchanan, J., da Costa, N.M., and Lucas Cheadle

Trends in Neurosciences.     2023

Neuron-glia communication through bona fide synapses

Lucas Cheadle

Nature Reviews Neuroscience.     2023

Integrated high-confidence and high-throughput approaches for quantifying synapse engulfment by oligodendrocyte precursor cells

Kahng, J.A., Xavier, A.M, Ferro, A., Auguste, Y.S.S., and Lucas Cheadle

Preprint.     2023

Oligodendrocyte precursor cells engulf synapses during circuit remodeling in mice

Auguste*, Y.S.S., Ferro*, A., Kahng, J.A., Xavier, A.M., Dixon, J.R., Vrudhula, U., Nichitiu, A.-S., Rosado, D., Wee, T.-L., Pedmale, U.V., and Lucas Cheadle

Nature Neuroscience.     2022

When the levee of sympathetic outflow breaks

Ferro, A., and Lucas Cheadle 

Immunity.     2022

Oligodendrocyte precursor cells engulf synaptic inputs in an experience- and microglia-dependent manner

Auguste, Y., Ferro, A., Dixon, J., Vrudhula, U., Kahng, J., Nichitiu, A., Lucas Cheadle

Preprint.      2022

Microglia, Cytokines, and Neural Activity: Unexpected Interactions in Brain Development and Function

Ferro, A., Auguste, Y., and Lucas Cheadle

Frontiers Immunology.    2021

Microglia and Fn14 regulate transcription and chromatin accessibility in developing neurons

Ferro, A., Vrudhula, U., Auguste, Y., Cheadle, L.

Preprint.     2021

Sensory experience engages microglia to shape neural connectivity through a non-phagocytic mechanism

Cheadle, L., Rivera, A.S., Phelps, J.S., Ennis, K.A., Stevens, B., Burkly, L.C., Lee, W-C.A., and Greenberg, M.E.

Neuron.     2021

Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling

Gunner, G., Cheadle, L.*, Johnson, K.*, Ayata, P., Badimon, A., Mondo, E., Nagy, A., Liu, L., Bemiller, S.M., Kim, K-W., Lira, S.A., Lamb, B.T., Tapper, A.R., Ransohoff, R.M., Greenberg, M.E., Schaefer, A., and Schafer, D.P.

Nature Neuroscience.    2019

Visual experience-dependent expression of Fn14 is required for retinogeniculate refinement

Cheadle, L.*, Tzeng, C.P.*, Kalish, B.T., Harmin, D.A., Rivera, S., Ling, E., Nagy, M.A., Hrvatin, S., Hu, L., Stroud, H., Burkly, L., Chen, C., and Greenberg, M.E.

Neuron.     2018

Single-cell analysis of experience-dependent transcriptomic states in mouse visual cortex

Hrvatin, S.*, Hochbaum, D.R.*, Nagy, M.A.*, Cicconet, M., Robertson, K., Cheadle, L., Zilionis, R., Ratner, A., Borges-Monroy, R., Klein, A.M., Sabatini, B.L., and Greenberg, M.E.

Nature Neuroscience.     2018

Single-cell transcriptomics of the developing lateral geniculate nucleus reveals insights into circuit assembly and refinement

Kalish, B.T.*, Cheadle, L.*, Hrvatin, S., Nagy, M.A., Rivera, S., Crow, M., Gillis, J., Kirchner, R., and Greenberg, M.E.

PNAS.      2018

Activity-dependent regulation of dendritic complexity by Semaphorin3A through Farp1

Cheadle, L. and Biederer, T.

The Journal of Neuroscience.     2014

The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and trans-synaptic organization

Cheadle, L. and Biederer, T.

Journal of Cell Biology.     2012